TG101209

TG101209 is a potent and small molecule JAK2-selective kinase inhibitor that has been shown effective in a wide variety of important disease and disease treatment schemes

JAK2 IC50 6nM; FLT3 25nM; RET 17nM; JAK3 169nM

CAS #: 936091-14-4

IUPAC Name: N-tert-butyl-3-[[5-methyl-2-[4-(4-methylpiperazin-1-yl)anilino] pyrimidin-4-yl]amino]benzenesulfonamide

InChI: InChI=1S/C26H35N7O2S/c1-19-18-27-25(29-20-9-11-22(12-10-20)33-15-13-32
(5)14-16-33)30-24(19)28-21-7-6-8-23(17-21)36(34,35)31-26(2,3)4/h6-12,
17-18,31H,13-16H2,1-5H3,(H2,27,28,29,30)

InChIKey: JVDOKQYTTYUYDV-UHFFFAOYSA-N

Canonical SMILES : CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)N4CCN(CC4)C

CID 16722832; SID 136367688