Anti-phospho AS160 (Ser318) Antibody
Availability: In Stock
Species Reactivity : Human, Mouse
Host : Sheep
Format : Affinity purified
Applications : WB
Alternative Names: TBC1 domain family member 4
AS160 (Akt substrate of 160 kDa), a Rab GTPase-activating protein, is an Akt substrate implicated in the regulation of GLUT4 translocation. Multiple Akt phosphorylation sites have been identified on AS160, with five sites showing increased phosphorylation following insulin treatment. Phosphorylation of AS160 by AMPK is involved in the regulation of contractionstimulated GLUT4 translocation. AS160 phosphorylation is impaired in some patients with type 2 diabetes. Symansis is proud to offer a phospho-specific antibody to AS160 a S318 to further AS160 research.