Anti-p70S6Kα, total Antibody

Catalog Number: 3009-1C
Availability: In Stock
Size: 100 µg
Uniprot Nu : P23443
Species Reactivity : Human, Mouse
Host : Sheep
Format : Affinity purified
Applications : WB
Alternative Names: S6K-beta-1, p70S6K1, p70S6KA

* Size(micrograms):






The mitogen-stimulated protein kinase p70 ribosomal protein S6 kinase 1 (S6K1) is a member of a family of serine/threonine protein kinases that phosphorylate the 40S ribosomal protein S6, thereby modulating the translation of ribosomal proteins and translation elongation factors. p70-S6K is activated in response to the phosphatidylinositol 3-kinase (PI3K) and mitogenactivated protein kinase (MAPK) pathways, and is required for progression through the cell cycle and for cell growth. Activation of p70-S6K is regulated by phosphorylation of seven different residues distributed throughout the protein. Symansis 3009-1C is a polyclonal sheep antibody raised to the C-terminus of human p70S6K protein. The antibody works excellently in western blots and is expected to work well in native applications as well but it is, as yet, untested in those applications.







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