Ro 31-8425, Bisindoylmaleimide X HCL/R0-31-8425
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Alternative Names: Ro 31-8425, Bisindoylmaleimide X HCL, R0-31-8425
A potent, cell-permeable, reversible, ATP-competitive, and selective protein kinase C inhibitor (IC50 = 15 nM for rat brain PKC). Exhibits some degree of isozyme specificity (IC50 = 8 nM for PKCa, 8 nM for PKCßI, 14 nM for PKCßII, 13 nM for PKC?, and 39 nM for PKCe).
HCL salt, CAS:145317-11-9