AP24534, AP-24534

Catalog Number: SY-AP24534
Availability: In Stock
Size: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg
CAS Number : 943319-70-8
Alternative Names: AP24534, AP-24534, Ponatinib

* Size:



AP24534 is active against pan-BCR-ABL (IC50=0.37nM) and mutated form (IC50=0.3-2.0nM), VEGFR2(IC50=1.5nM), FGFR1(IC50=2.2nM), PDGFR (IC50=1.1nM) and LYN (IC50=0.24nM). AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance.  

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