IL-10

Interleukin 10 (IL-10) is a pleiotropic cytokine that regulates multiple immune responses through actions on T-cells, B-cells, macrophages/monocytes and antigen presenting cells (APC). In general IL-10 skews the immune response from TH1 to TH2.

Densitometry of protein isoforms visualised by 2-DE. Spot trains are normal in human proteins and highlight the presence of multiple isoforms which differ according to their level of post-translational modification. The triangle indicates the theoretical MW and pI of the protein.

1. Mocellin S, et al. (2004) Cytokine Growth Factor Rev. 15: 61-76.