CC-401, CC401

Catalog Number: SY-CC-401
Availability: In Stock
Size: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg
CAS Number : 395104-30-0
Alternative Names: CC401

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A second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. Based on the chemistry of SP600125, another anthrapyrazolone inhibitor of JNK, CC-401 competitively binds the ATP binding site of JNK, resulting in inhibition of the phosphorylation of the N-terminal activation domain of transcription factor c-Jun; decreased transcription activity of c-Jun; and a variety of cellular effects including decreased cellular proliferation


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