Cripto-1 - Fc Chimera
Availability: In Stock
Species Reactivity : Human
Host : Human, HEK Cell Expessed
Symansis' purified Cripto-1 - Fchcx Chimera has N- and O-linked oligosaccharides, shown by a drop in observed MW on SDS-PAGE after treatment with PNGase F and a further drop after treatment with a glycosidase cocktail. Symansis' Cripto-1 - Fchcx Chimera consists of 5-30% carbohydrate by weight.
Densitometry of protein isoforms visualised by 2-DE. Spot trains are normal in human proteins and highlight the presence of multiple isoforms which differ according to their level of post-translational modification. The triangle indicates the theoretical MW and pI of the protein.
1D SDS-PAGE of Symansis' hcx protein before and after treatment with glycosidases to remove oligosaccharides. A drop in the observed MW after treatment indicates the presence of glycosylation. For more details, please see product sheet.
1. Strizzi et al. (2005) Oncogene 24:5731-5741