TNF- α, Carrier free formulation

Catalog Number: 8005C/CF
Availability: In Stock
Size: 5 µg
Uniprot Nu : P01375
Species Reactivity : Human
Host : Human, HEK Cell Expessed

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TNF-a is N-glycosylated, and the glycosylated form exhibits distinct biological activity from the non-glycosylated form.

Densitometry of protein isoforms visualized by 2-DE. Spot trains are normal in human proteins and highlight the presence of multiple isoforms which differ according to their level of post-translational modification. The triangle indicates the theoretical MW and pI of the protein.

Tumor necrosis factor alpha (TNF-a) and the structurally related lymphotoxin-alpha are pro-inflammatory cytokines produced by a variety of immune and non-immune cells in response to multiple stimuli, including bacterial products, viral infections, and T- and B-cell activation.

1. Mikuls TR & Weaver AL (2003) Curr Rheumatol Rep. 5: 270-7.
2. Koyama Y, et al. (1992) Biochim Biophys Acta 1132: 188-94.

 

 

 

Tags: P01375


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