NGF R (209 aa) - Fc Chimera

Catalog Number: ZQ9
Availability: In Stock
Size: 40 µg
Uniprot Nu : P08138
Species Reactivity : Human
Host : Human, HEK Cell Expessed

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Symansis' purified NGF R - Fc Chimerahcx has N-linked and O-linked oligosaccharides, shown by a drop in observed MW on SDS-PAGE after treatment with PNGase F and a further drop in observed MW on SDS-PAGE after treatment with a glycosidase cocktail. Symansis' NGF R - Fc Chimerahcx consists of 25-45% carbohydrate by weight.

Densitometry of protein isoforms visualised by 2-DE. Spot trains are normal in human proteins and highlight the presence of multiple isoforms which differ according to their level of post-translational modification. The triangle indicates the theoretical MW and pI of the protein.

1D SDS-PAGE of Symansis' hcx protein before and after treatment with glycosidases to remove oligosaccharides. A drop in the observed MW after treatment indicates the presence of glycosylation.

1. Salehi A, et al. (2004) J Neural Transm. 111: 323-45.

 

 

 

Tags: ZQ9, P08138


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