IL-7 R α - Fc Chimera

Catalog Number: 4107
Availability: In Stock
Size: 25 µg
Uniprot Nu : P16871
Species Reactivity : Human
Host : Human, HEK Cell Expessed

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Symansis' purified IL-7 R alpha - Fc Chimerahcx has N-linked oligosaccharides, shown by a drop in observed MW on SDS-PAGE after treatment with PNGase F, and may have O- and/or C-linked oligosaccharides. Symansis' IL-7 R alpha - Fc Chimerahcx consists of 28-40% carbohydrate by weight.

Densitometry of protein isoforms visualised by 2-DE. Spot trains are normal in human proteins and highlight the presence of multiple isoforms which differ according to their level of post-translational modification. The triangle indicates the theoretical MW and pI of the protein.

1D SDS-PAGE of Symansis' hcx protein before and after treatment with glycosidases to remove oligosaccharides. A drop in the observed MW after treatment indicates the presence of glycosylation.

1. Fry TJ & Mackall CL (2005) J Immunol. 174: 6571-6.

 

 

 

Tags: 4107D, 4107H, P16871


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